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Chem Biol. 1995 Jan;2(1):1-5.

The chemistry of scrapie infection: implications of the 'ice 9' metaphor.

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1
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, USA.

Abstract

The transmissible spongiform encephalopathies pose an increasing problem for animal, and perhaps human, health. The infectious agent seems to lack a nucleic acid component, posing the question of how it can reproduce. A model of reproduction by nucleated polymerization suggests a number of novel approaches to the problem.

PMID:
9383397
[Indexed for MEDLINE]
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