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Infect Dis Clin North Am. 1997 Sep;11(3):513-29.

Bacterial virulence in urinary tract infection.

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Department of Medical Microbiology, Lund University, Sweden.


Urinary tract infections (UTI) are caused by a variety of gram-negative bacteria that ascend into the urinary tract and establish bacteriuria often at levels greater than or equal to 10(5) bacteria/ mL of urine. Escherichia coli dominate as the causative agent in all patient groups, with Staphylococcus saprophyticus as the second most common, accounting for about 10% to 30% of the infections in young adult women depending on the season. This article covers the pathogenesis and inflammatory response of UTI and the virulence factors of uropathogenic E. coli.

[Indexed for MEDLINE]

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