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Chest. 1997 Oct;112(4):1050-4.

Risk factors for infection by Acinetobacter baumannii in intubated patients with nosocomial pneumonia.

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1
Pulmonary and Critical Care Department, Hospital Italiano, Montevideo, Uruguay.

Abstract

STUDY OBJECTIVE:

To investigate the epidemiology of infection by Acinetobacter baumannii in patients with ventilator-associated pneumonia (VAP).

DESIGN:

Prospective clinical study.

SETTING:

Three medical-surgical ICUs in teaching hospitals.

PATIENTS:

We followed up 707 mechanically ventilated patients and 148 episodes of VAP with etiologic diagnosis.

RESULTS:

A baumannii was isolated in 12 (8.1%) episodes in 148 patients. Five of these episodes were directly responsible for death. Using logistic regression analysis, the risk of VAP due to A baumannii was found to be high in patients with neurosurgery (odds ratio [OR]=10.03; 95% confidence interval [CI]=1.55 to 64.90), ARDS (OR=9.73; 95% CI=1.60 to 59.24), head trauma (OR=5.17; 95% CI=0.88 to 30.34), and large-volume pulmonary aspiration (OR=2.90; 95% CI=0.80 to 10.53).

CONCLUSIONS:

Intubated patients who develop pneumonia and have any of the above factors are at an increased risk of Acinetobacter infection.

PMID:
9377916
[Indexed for MEDLINE]
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