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Br J Rheumatol. 1997 Sep;36(9):1012-5.

Sesame oil in injectable gold: two drugs in one?

Author information

1
Department of Rheumatology, University Hospital Leiden, The Netherlands.

Abstract

To investigate the potential anti-inflammatory effects of sesame oil, which is present in the injectable gold preparation Auromyose, the synthesis of tumour necrosis factor alpha (TNF-alpha), prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) by in vitro stimulated blood cells was measured before, during and after 12 weeks of dietary supplementation with 18 g of sesame oil daily in 11 healthy male volunteers. Neither TNF-alpha, PGE2 nor LTB4 production levels showed statistically significant changes during the 12 weeks of dietary supplementation with sesame oil. These results do not suggest an anti-inflammatory effect of sesame oil as present in injectable gold preparations which are used in the treatment of rheumatoid arthritis.

PMID:
9376977
DOI:
10.1093/rheumatology/36.9.1012
[Indexed for MEDLINE]

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