Purpose: To report macular ischemia as a cause of decreased vision in a patient with acquired immunodeficiency syndrome (AIDS).
Methods: A 50-year-old man with AIDS who had previously diagnosed human immunodeficiency virus retinopathy and peripheral cytomegalovirus retinitis was initially examined with decreased vision in both eyes. He underwent complete systemic and ocular evaluation, fundus photography, and fluorescein angiography.
Result: Fluorescein angiography disclosed irregular enlargement of the foveal avascular zone in both eyes.
Conclusions: Macular ischemia may cause decreased vision in patients with AIDS and can be detected by fluorescein angiography.