Factors influencing the photo-reproduction of hydroa vacciniforme lesions

Photodermatol Photoimmunol Photomed. 1997 Jun;13(3):98-102. doi: 10.1111/j.1600-0781.1997.tb00124.x.

Abstract

Hydroa vacciniforme vesicles can be reproduced experimentally with repetitive UVA irradiations, but this photo-reproduction is not constant. The aim of this study was to search for the factors that influence photo-reproduction. To reproduce hydroa vacciniforme lesions six patients underwent repetitive UVA and polychromatic irradiations on the back. In four patients out of six, UVA irradiation with high doses induced papulo-vesicular lesions. Photo-induced lesions were very close to those induced by sunlight. Photo-reproduction failed when phototesting was done after or shortly before remission. Therefore, the absence of photo-reproduction appears to be a good prognostic factor.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Cicatrix / pathology
  • Erythema / etiology
  • Erythema / physiopathology
  • Female
  • Humans
  • Hydroa Vacciniforme / etiology*
  • Hydroa Vacciniforme / pathology
  • Hydroa Vacciniforme / physiopathology
  • Male
  • Necrosis
  • Prognosis
  • Pruritus / etiology
  • Radiation Dosage
  • Recurrence
  • Remission, Spontaneous
  • Skin / pathology
  • Skin Tests / methods
  • Sunlight / adverse effects
  • Ultraviolet Rays / adverse effects*