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Brain Res Dev Brain Res. 1997 Oct 20;103(1):95-7.

Expression of potassium channels in gerbil outer hair cells during development does not require neural induction.

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1
Auditory Physiology Laboratory, Hugh Knowles Center, Northwestern University, Evanston, IL, USA. z-he2@nwu.edu

Abstract

Mammalian outer hair cells (OHCs) contain Ca and K channels in their synaptic pole. We questioned if the ontogeny of potassium currents of OHCs depends on the neural induction of early afferent contact. By recording whole-cell currents of OHCs grown in organotypic cultures deprived of afferent innervation, we show that a Ca-activated K channel is expressed in these cells, suggesting that the ontogeny of the K channel is an intrinsic process.

PMID:
9370065
[Indexed for MEDLINE]
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