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Curr Opin Immunol. 1997 Oct;9(5):702-8.

Prospects for adoptive T cell therapy.

Author information

1
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA.

Abstract

Since the establishment of methods to isolate genes encoding cytotoxic T lymphocyte defined tumor antigens, several antigens have been identified and characterized for suitability as target antigens for immunotherapy. The development of innovative strategies to generate T cells targeting these antigens and lessons learned from clinical trials of adoptive immunotherapy of viral diseases should facilitate the design of clinical trials for specific adoptive immunotherapy of cancer.

PMID:
9368780
DOI:
10.1016/s0952-7915(97)80052-0
[Indexed for MEDLINE]

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