Format

Send to

Choose Destination
Immunol Today. 1997 Oct;18(10):478-82.

Th1-type immunity is incompatible with successful pregnancy.

Author information

1
Dept. of Microbiology, Faculty of Medicine, Kuwait University, Kuwait. Raj@hscc.kuniv.edu.kw

Abstract

Several years ago, the rather provocative question was raised: is successful pregnancy a T helper 2 (Th2) phenomenon? Implicit in this argument is the corollary that unsuccessful pregnancy is a Th1-type situation. Here, evidence from murine and human pregnancy is presented to show that, since Th1-type cytokines mediate pregnancy loss, a shift towards Th1-type immunity may help resolve 'unexplained' pregnancy failure.

PMID:
9357139
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center