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Curr Opin Biotechnol. 1997 Oct;8(5):583-9.

Adenoviral vectors for gene transfer.

Author information

1
GenVec Inc., Rockville, MD 20852, USA. kovesdi@genvec.com

Abstract

Adenoviruses began to be developed into highly effective gene expression vectors in the early 1980s. Recently, the increased interest in utilizing this transfer system in vivo has posed new problems for heterologous gene-transfer, spurring a renewed effort in the field of vector development toward solving the structural, immunological and targeting problems posed by gene therapy applications.

PMID:
9353227
DOI:
10.1016/s0958-1669(97)80033-x
[Indexed for MEDLINE]

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