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Obstet Gynecol. 1976 Jul;48(1):27-30.

Acidosis, local anesthetics, and the newborn.

Abstract

Four newborn infants were studied following maternal epidural block with lidocaine or mepivacaine. Each of these neonates, born with a pH of 7.23 or below in the umbilical vein blood, showed an elevated fetal-to-maternal concentration ratio, a possible manifestation of ion trapping of a weak base.

PMID:
934571
[Indexed for MEDLINE]
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