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Biosci Rep. 1997 Jun;17(3):259-72.

Generating, partitioning, targeting and functioning of superoxide in mitochondria.

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1
State Key Laboratory of Biomembrane and Membrane Biotechnology, Chinese Academy of Sciences, Beijing, China.

Abstract

Recently, we proposed a hypothetical model of coexistence of "Reactive oxygen cycle" with Q cycle and H+ cycle in mitochondrial respiratory chain to combine both processes of univalent electron leak for production of superoxide and of proton leak across inner mitochondrial membrane. This review presents a more detailed description of this model and summaries the supporting experimental evidence obtained.

PMID:
9337481
[Indexed for MEDLINE]
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