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Ophthalmology. 1997 Oct;104(10):1701-7.

In vitro flow testing of glaucoma drainage devices.

Author information

1
U.S. Food and Drug Administration, Rockville, Maryland 20852, USA.

Abstract

OBJECTIVE:

The study was intended to determine methods that could evaluate in vitro the flow characteristics of glaucoma drainage devices.

DESIGN:

Two test methods were used: (1) a gravity-driven flow test and (2) a syringe-pump-driven flow test. Eighteen devices, both valved and nonvalved, from 4 manufacturers were evaluated for their hydrodynamic resistance and the pressure at which the flow becomes 0.

OUTCOME:

Results show a wide variation in device performance, indicating a strong need for enhanced quality control procedures in the device manufacturing process.

CONCLUSION:

A gravity-driven flow test provides a reasonably quick test of both resistance and closing pressure, which might be useful as a manufacturing line test. The syringe-driven flow test requires more time but provides additional insight into device performance, and, therefore, might be useful as a design validation test.

PMID:
9331212
DOI:
10.1016/s0161-6420(97)30077-3
[Indexed for MEDLINE]

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