Lhermitte-Duclos disease associated with Cowden's disease--case report

Neurol Med Chir (Tokyo). 1997 Sep;37(9):697-700. doi: 10.2176/nmc.37.697.

Abstract

A 49-year-old Japanese male with Lhermitte-Duclos disease subsequently developed a very rare association with Cowden's disease. Partial tumor removal established the diagnosis of Lhermitte-Duclos disease. Follow-up examinations discovered the presence of Cowden's disease. Long-term follow-up of patients with Lhermitte-Duclos disease is essential to identify signs of Cowden's disease, which carries the risk of developing malignancy.

Publication types

  • Case Reports

MeSH terms

  • Cerebellar Neoplasms / genetics*
  • Cerebellar Neoplasms / pathology
  • Cerebellar Neoplasms / surgery
  • Cerebellum / pathology
  • Cerebellum / surgery
  • Chromosome Aberrations / genetics
  • Chromosome Disorders
  • Endoscopy, Gastrointestinal
  • Ganglioneuroma / genetics*
  • Ganglioneuroma / pathology
  • Ganglioneuroma / surgery
  • Gastrointestinal Neoplasms / genetics
  • Gastrointestinal Neoplasms / pathology
  • Gastrointestinal Neoplasms / surgery
  • Genes, Dominant / genetics
  • Hamartoma Syndrome, Multiple / genetics*
  • Hamartoma Syndrome, Multiple / pathology
  • Hamartoma Syndrome, Multiple / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Polyps / genetics
  • Polyps / pathology
  • Polyps / surgery
  • Tomography, X-Ray Computed