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J Neurol Neurosurg Psychiatry. 1997 Sep;63(3):373-5.

Schizencephaly associated with psychosis.

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1
Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania, Philadelphia 19104, USA.

Abstract

Schizencephaly is a rare disorder of brain development resulting in the formation of abnormal unilateral or bilateral clefts in the cerebral hemispheres. It is often accompanied by partial seizures, mental retardation, and hemiparesis. Two patients are described with clear psychotic symptoms with either unilateral or bilateral schizencephaly. The implications of the association between schizencephaly and psychosis in these patients for understanding the biology of the psychoses are discussed.

PMID:
9328256
PMCID:
PMC2169691
[Indexed for MEDLINE]
Free PMC Article
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