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Curr Opin Nephrol Hypertens. 1997 Sep;6(5):440-6.

Sodium-hydrogen exchange in renal epithelia: mechanisms of acute regulation.

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Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235-8856, USA.


Five isoforms of sodium-hydrogen exchangers are present in the kidney. Specific isoforms serve specialized functions and are strategically located in polarized distributions in different nephron segments. This review updates understanding of the renal distribution and highlights some of the recent advances in understanding the mechanisms of acute regulation of sodium-hydrogen exchangers in the kidney.

[Indexed for MEDLINE]

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