Abstract
Effects of antibiotics and chemotherapeutics on the interaction between the HL-A antigens and the corresponding lymphocytotoxic sera vary from case to case. Streptomycin, oleandomycin, cephaloridine and kanamycin completely inhibit the cytotoxic reaction when added in the first or second stage of the test. Cytembena weakens the reaction while chlortetracyclin exhibits various effects. The rest of the drugs under investigation proved ineffective.
MeSH terms
-
Anti-Bacterial Agents / pharmacology
-
Antigen-Antibody Reactions / drug effects*
-
Antilymphocyte Serum*
-
Cephaloridine / pharmacology
-
HLA Antigens*
-
Histocompatibility Antigens*
-
Humans
-
Kanamycin / pharmacology
-
Lymphocytes / immunology*
-
Oleandomycin / pharmacology
-
Pharmacology
-
Streptomycin / pharmacology
Substances
-
Anti-Bacterial Agents
-
Antilymphocyte Serum
-
HLA Antigens
-
Histocompatibility Antigens
-
Kanamycin
-
Cephaloridine
-
Oleandomycin
-
Streptomycin