Format

Send to

Choose Destination
Cell Tissue Res. 1997 Nov;290(2):209-15.

Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system.

Author information

1
Department of Molecular Oncology, Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, NJ 08543-4000, USA.

Abstract

The Eph family of tyrosine protein kinase receptors and their cognate ligands, a family of membrane-bound molecules known as ephrins, have been implicated in diverse biological processes, such as axon guidance, the formation of topographic neural projections, axon fasciculation, the regionalization of the central nervous system, and cell migration. The recent generation of mutant mice lacking some of these receptors has made possible the dissection of the role that these molecules play in the development of the mammalian nervous system.

PMID:
9321682
DOI:
10.1007/s004410050925
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center