Format

Send to

Choose Destination
Endocrinol Metab Clin North Am. 1997 Sep;26(3):539-51.

alpha-Glucosidase inhibitors.

Author information

1
Department of Endocrinology, Metabolism, and Diabetes, State University of New York, Health Science Center at Brooklyn, New York, USA.

Abstract

Alpha-glucosidase inhibitors are antihyperglycemic agents that lower blood glucose by delaying the digestion and absorption of complex carbohydrates. They are competitive inhibitors of the enzymes in the brush border of enterocytes that cleave eligosaccharides to monosaccharides. Their major action is to reduce the rise of postprandial plasma glucose. In non-insulin-dependent diabetes mellitus patients, these inhibitors decrease postprandial plasma glucose by 40 to 50 mg/dL and hemoglobin A1C by 0.5% to 1.0%.

PMID:
9314014
DOI:
10.1016/s0889-8529(05)70266-8
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center