Send to

Choose Destination
FEMS Microbiol Lett. 1997 Sep 15;154(2):385-8.

Mercury induces multiple antibiotic resistance in Escherichia coli through activation of SoxR, a redox-sensing regulatory protein.

Author information

Departamento de Microbiología, LUSARA, México, D.F., Mexico.


Sub-inhibitory mercury concentrations are capable of partially activating SoxR, as shown by the augmented expression of a soxS'::lacZ fusion, and a diminished sensitivity to antibiotics caused by mercury treatment. Mercury may elevate the intracellular concentration of superoxide or perhaps act as a putative metal ligand for SoxR.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center