Format

Send to

Choose Destination
Curr Opin Genet Dev. 1997 Aug;7(4):537-42.

Notch signalling in development: on equivalence groups and asymmetric developmental potential.

Author information

1
Institut de Génétique et de Biologie Cellulaire et Moléculaire, CNRS/INSERM/ULP, Illkirch, France. psimpson@igbmc.u-strasbg.fr

Abstract

Notch-mediated lateral signalling takes place between equivalent cells that then adopt alternative fates. An example is the epidermal-neural choice in the Drosophila neuro-ectoderm. Sometimes this choice is random. Sometimes it is biased to a preferred cell by an extrinsic signal. Sometimes the neural precursor is predetermined. A stochastic outcome is probably older in evolutionary terms.

PMID:
9309187
DOI:
10.1016/s0959-437x(97)80083-4
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center