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Curr Opin Genet Dev. 1997 Aug;7(4):519-23.

Left-right asymmetry in vertebrates.

Author information

1
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Abstract

All vertebrates develop with a distinct, invariant, left-right (L-R) body asymmetry. Recently, a number of molecules have been shown to be expressed asymmetrically with respect to the L-R axis during early embryogenesis. The temporal expression patterns of these molecules, in combination with embryo manipulation and genetic experiments, indicate that they may represent elements of a conserved pathway governing embryonic handedness.

PMID:
9309184
DOI:
10.1016/s0959-437x(97)80080-9
[Indexed for MEDLINE]

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