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Can J Microbiol. 1997 Aug;43(8):770-3.

Nematophin, a novel antimicrobial substance produced by Xenorhabdus nematophilus (Enterobactereaceae).

Author information

1
Department of Biological Sciences, Simon Fraser University, Vancouver, B.C., Canada. jli@sfu.ca

Abstract

A new antibiotic, nematophin, was isolated from strain BC1 of Xenorhabdus nematophilus and detected in all strains of X. nematophilus studied. Its structure is fully established as 3-indoleethyl (3'-methyl-2'-oxo)pentanamide by extensive spectroscopic study. The production of nematophin is affected by the strain type and culture conditions. The compound shows strong in vitro bioactivity against a series of fungal and bacterial species.

PMID:
9304787
DOI:
10.1139/m97-110
[Indexed for MEDLINE]

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