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J Am Vet Med Assoc. 1997 Sep 15;211(6):719-22.

Effect of stanozolol on body composition, nitrogen balance, and food consumption in castrated dogs with chronic renal failure.

Author information

1
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan 66506, USA.

Abstract

OBJECTIVE:

To determine the effect of stanozolol on body composition, nitrogen balance, and food consumption in castrated dogs with chronic renal failure.

DESIGN:

Blinded crossover trial.

ANIMALS:

22 castrated Beagles with experimentally induced chronic renal failure.

PROCEDURE:

Dogs were divided into 2 groups of 11 dogs each. During each of two 6-week treatment periods, dogs in 1 group received stanozolol, and those in the other group received a control agent. Nitrogen balance, body composition, and food consumption were determined.

RESULTS:

During administration of stanozolol, the amount of food consumed per dog, lean body mass, and nitrogen balance increased. Stanozolol did not have a significant effect on body fat, bone mineral content, or food consumption per kilogram of body weight.

CLINICAL IMPLICATIONS:

For dogs with mild-to-moderate, nonuremic, experimentally induced, chronic renal failure, stanozolol had positive effects on nitrogen balance and lean body mass.

Comment in

PMID:
9301741
[Indexed for MEDLINE]

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