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J Comp Physiol B. 1997 Aug;167(6):438-43.

Effect of manipulation of the renin-angiotensin system in control of drinking in juvenile Atlantic salmon (Salmo salar L) in fresh water and after transfer to sea water.

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1
Department of Biological Sciences, University of Dundee, Scotland, UK.

Abstract

Drinking in Atlantic salmon (Salmo salar) juveniles was investigated in fresh water and following transfer to sea water. There was a significant effect of fish size on drinking, and smolts (20-30 g) imbibed about ten times less water than alevins of 0.2-0.3 g. Freshwater smolts drank at a rate of 0.15 +/- 0.03 ml.kg-1.h-1 and administration of doses of 10 or 20 mg.kg-1 of papaverine (stimulator of the renin-angiotensin system RAS) or [Asn1, Val5]-Angiotensin II (0.4 mumol.kg-1) resulted in significant increases in drinking, while administration of the angiotensin converting enzyme inhibitor, enalapril (50 mg.kg-1) had no effect on drinking. Transfer of Atlantic salmon smolts to 1/3, 2/3 and full strength sea water resulted in significant increases in drinking to 1.06 +/- 0.12, 1.24 +/- 0.0.16 and 3.89 +/- 0.28 ml.kg-1.h-1, respectively. In sea water, stimulation of the endogenous RAS by administration of papaverine (20 mg.kg-1) resulted in a 20% increase in drinking, while administration of enalapril to doses of 50 and 200 mg.kg-1 lowered drinking to 1.99 +/- 0.48 and 0.32 +/- 0.06 ml.kg-1.h-1, respectively. All treatments were without effect on blood plasma levels of Na+ and Cl- in fresh water, while in sea water smolts both stimulation and inhibition of drinking resulted in hemoconcentration of Na+ and Cl-. The role of the renin angiotensin system in control of drinking and hydromineral balance in Atlantic salmon is discussed.

PMID:
9286092
DOI:
10.1007/s003600050094
[Indexed for MEDLINE]

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