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Mol Cell Biochem. 1997 Jul;172(1-2):23-35.

Retroviral techniques for studying organogenesis with a focus on heart development.

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  • 1Department of Cell Biology and Anatomy, Cornell University Medical College, New York 10p6021, USA.


The study of development has been revolutionized by the application of molecular techniques, which make it possible to identify factors involved in the developmental process. However, in order to correctly assess the contribution of these growth factors, transcription factors, receptors or signaling molecules, it is necessary to study them in the animal as a whole; it is not enough to conclude that they must be important based on their expression patterns.

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