A case of Leuconostoc cremoris bacteremia in a patient with burn wounds over 45% of the body surface is presented. Leuconostoc bacteremia has not previously been reported in burn patients. The predisposing factors in this case were severe burn wounds resulting in immunocompromise, presence of both intravenous and enteral feeding catheters, several surgical interventions and previous treatment with imipenem plus amikacin. The patient was successfully treated with ampicillin 2 g l.v. every 6 hours for 21 days. Infection with Leuconostoc should be suspected when vancomycin-resistant organisms resembling streptococci are isolated.