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Dev Biol Stand. 1997;89:77-81.

Severe adverse events in the Italian and Stockholm I pertussis vaccine clinical trials.

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Istituto Superiore di Sanità, Rome, Italy.


The rates of severe side reactions observed in Stockholm I and Italian Trials are reported. Children vaccinated with the same DTPwc in both trials experienced high fever and persistent crying more frequently than in any other group, while similar rates for all the severe side reactions were observed among DTaPs and DT vaccines. Recipients of different DTaP vaccines showed similar rates of severe reactions, which did not differ from recipients of DT vaccines, either in Sweden or Italy.

[Indexed for MEDLINE]

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