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Clin Chem. 1997 Aug;43(8 Pt 2):1500-6.

Hepatitis B: diagnosis, prevention, and treatment.

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Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.


Hepatitis B virus (HBV) infection occurs worldwide and is an important cause of acute and chronic viral hepatitis in the US. In this review, I describe the virus, risk factors for infection, clinical features of infection, results of laboratory tests during infection, and standard and emerging treatment for chronic infection. Although 95% of adult patients recover completely from HBV infection, 90% of children < or = 4 years of age develop chronic infection. Active vaccination is highly efficacious.

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