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Curr Opin Cell Biol. 1997 Aug;9(4):527-33.

The trans-Golgi network: a late secretory sorting station.

Author information

1
Division of Hematology, Washington University School of Medicine, St Louis, MO 63110, USA.

Abstract

Proteins synthesized on membrane-bound ribosomes are transported through the Golgi apparatus and, on reaching the trans-Golgi network, are sorted for delivery to various cellular destinations. Sorting involves the assembly of cytosol-oriented coat structures which preferentially package cargo into vesicular transport intermediates. Recent studies have shed new light on both the molecular machinery involved and the complexity of the sorting processes.

PMID:
9261049
DOI:
10.1016/s0955-0674(97)80029-4
[Indexed for MEDLINE]

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