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J Intern Med. 1997 Jul;242(1):61-6.

Hyaluronan in skin.

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Department of Dermatology, University Hospital, Uppsala, Sweden.


Because of the abundance of hyaluronan in skin, interest was early focused on variation in the content of the polysaccharide in various pathological conditions of this tissue. A large amount of early work utilized histological techniques of insufficient specificity but recent developments of specific analytical and staining methods for hyaluronan have supplied new data on its presence and possible role in skin disorders.

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