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Eur J Clin Microbiol Infect Dis. 1997 Jun;16(6):458-60.

In vitro activity of trimethoprim against Borrelia burgdorferi.

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1
Department of Medicine, Karl-Franzens University, Graz, Austria.

Abstract

A new culture medium has been developed to evaluate the activity of trimethoprim and sulfamethoxazole against Borrelia burgdorferi in vitro. In this specially modified Barbour-Stoenner-Kelly medium, in which antagonizing substances were reduced to a minimum, trimethoprim was more active against Borrelia burgdorferi than against a sensitive strain of Escherichia coli, but sulfamethoxazole was not active against Borrelia burgdorferi.

PMID:
9248750
[Indexed for MEDLINE]

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