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Neurosci Res. 1997 Jul;28(3):269-73.

Developmental expression of calretinin in the medial basal hypothalamus and amygdala from male and female rats.

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1
Department of Zoology, Brigham Young University, Provo, UT 84602, USA. EDLEPHAR@ACD1.BYU.EDU

Abstract

Developmental expression of calretinin in the medial basal hypothalamic (MBH) and amygdala region was examined by Western analysis. Males displayed significantly higher calretinin levels compared to females in the MBH (but not the amygdala) on gestational day 19 and 20. These data imply that hormonal factors may regulate developmental MBH calretinin expression. In turn, sexually dimorphic brain structures might be influenced by calretinin levels that can alter sexually dimorphic patterns of steroidogenesis, cellular migration or programmed cell loss mechanism(s) during neuronal development by modulating intracellular calcium concentrations.

PMID:
9237275
[Indexed for MEDLINE]
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