Abstract
Systemic lupus erythematosus (SLE) frequently involves the central nervous system. The clinical presentation is highly variable and heterogeneous. The involvement of the central nervous system is often reflected in minor or major neuropsychiatric symptoms. We describe three cases of this neuropsychiatric lupus erythematosus. A variety of laboratory tests are essential in order to establish the correct diagnosis of neuropsychiatric SLE. We discuss the usefulness of magnetic resonance imaging in both a diagnostic setting and as a tool for improving the understanding of the pathogenesis of neuropsychiatric SLE.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Brain Diseases / diagnosis
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Brain Diseases / drug therapy
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Brain Diseases / etiology*
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Cognition Disorders / diagnosis
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Cognition Disorders / drug therapy
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Cognition Disorders / etiology
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Diagnosis, Differential
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Epilepsy / diagnosis
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Epilepsy / drug therapy
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Epilepsy / etiology
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Female
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Humans
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Lupus Erythematosus, Systemic / complications
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Lupus Erythematosus, Systemic / diagnosis
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Lupus Erythematosus, Systemic / psychology*
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Magnetic Resonance Angiography
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Magnetic Resonance Imaging
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Mental Disorders / diagnosis
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Mental Disorders / drug therapy
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Mental Disorders / etiology*
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Middle Aged
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Paranoid Disorders / diagnosis
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Paranoid Disorders / drug therapy
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Paranoid Disorders / etiology
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Psychotic Disorders / diagnosis
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Psychotic Disorders / drug therapy
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Psychotic Disorders / etiology