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Trends Microbiol. 1997 Jul;5(7):276-81.

Antiviral activity of cyclopentenone prostanoids.

Author information

1
Institute of Experimental Medicine, CNR, Rome, Italy. santoro@biocell.irmkant.rm.cnr.it

Abstract

Cyclopentenone prostanoids inhibit virus replication by turning on an intracellular defence response that involves the induction of cytoprotective heat-shock proteins, the modification of viral glycoprotein maturation and the control of NF-kappa B activation. These molecules represent an interesting model for the development of novel antiviral drugs that can affect different targets during the virus life cycle.

PMID:
9234510
DOI:
10.1016/S0966-842X(97)01066-4
[Indexed for MEDLINE]
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