Format

Send to

Choose Destination
Trends Microbiol. 1997 Jul;5(7):272-6.

How the Listeria monocytogenes ActA protein converts actin polymerization into a motile force.

Author information

1
Dept of Molecular Biology, Princeton University, NJ 08544-1014, USA.

Abstract

The ActA protein is an essential determinant of pathogenicity that is responsible for the actin-based motility of Listeria monocytogenes in mammalian cells and cell-free extracts. ActA appears to control at least four functions that collectively lead to actin-based motility: (1) initiation of actin polymerization, (2) polarization of ActA function, (3) transformation of actin polymerization into a motile force and (4) acceleration of movement mediated by the host protein profilin.

PMID:
9234509
DOI:
10.1016/S0966-842X(97)01048-2
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center