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Ter Arkh. 1997;69(3):31-3.

[The effect of polyunsaturated fatty acids of the omega-3 class on the late phase of the allergic reaction in bronchial asthma patients].

[Article in Russian]


Placebo-controlled study of changes in the course of atopic bronchial asthma (ABA) induced by supplement of the diet with polyunsaturated fatty acids of omega-3 class in 13 patients compared to placebo-treated subjects allowed the conclusion on significant attenuation of late allergic response in patients who had taken eiconol for two weeks. The effects of the acids are explained by a comparative replacement of arachidonic acid in the membranes of cell effectors of the inflammation with omega-3 fatty acids leading to inhibition of production of inflammation lipid mediators.

[Indexed for MEDLINE]

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