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Curr Opin Genet Dev. 1997 Jun;7(3):392-7.

The plakin family: versatile organizers of cytoskeletal architecture.

Author information

1
Keratinocyte Laboratory, Imperial Cancer Research Fund, London, UK.

Abstract

Desmoplakin, plectin, bullous pemphigoid antigen 1 and envoplakin are four sequence-related proteins--recently named the plakin family--that localize to intermediate filaments and filament attachment sites at the plasma membrane. New interest in the plakins has been stimulated by the discoveries that they can link different cytoskeletal elements together and that loss of plakin function can cause diseases of the skin and other tissues.

PMID:
9229116
DOI:
10.1016/s0959-437x(97)80154-2
[Indexed for MEDLINE]

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