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Chem Biol. 1997 Jun;4(6):409-14.

RNA as a drug target.

Author information

1
Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, New Frontiers Science Park (North), Third Avenue, Harlow, Essex, CM19 5AW, UK. neil_pearson-1@sbphrd.com

Abstract

Historically, the pharmaceutical industry has focused on proteins, rather than nucleic acids, as drug targets. But recent advances in the fields of RNA synthesis, structure determination and therapeutic target identification make the systematic exploitation of RNA as a drug target a realistic goal.

PMID:
9224569
DOI:
10.1016/s1074-5521(97)90192-7
[Indexed for MEDLINE]
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