The response of bulbar respiratory neurons and the total inspiration to stimulation of the limbic cortex and hypothalamus was not identical as a result of different sensitivity of the studied structures. The hypothalamus exerts mainly facilitating influence both in norm and at the maximal altitude (7500-8000 m). The limbic cortex exerts mainly inhibitory influence. At the maximal altitude no typical reactions of the respiratory neurons and the total respiration were observed in response to stimulation.