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Rev Prat. 1997 May 15;47(10):1083-7.

[Chorea and Huntington's disease].

[Article in French]

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INSERM U 289 et Fédération de neurologie Hôpital de la Salpêtrière, Paris.


The causes of chorea are numerous and it is convenient to distinguish hereditary chorea and acquired syndromes with chorea. Huntington's disease represents the most typical disorder with chorea and the clinical diagnosis must be considered if there is chorea intellectual decline and autosomal dominant inheritance. The availability of molecular analysis for diagnostic confirmation shows that the clinical diagnosis in experienced centers is very accurate. Predictive testing involves several ethical problems, especially related to the severity of the disease and its absence of treatment. The other causes of hereditary chorea are less frequent and specific clinical contexts are evoqual of acquired choreas.

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