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Brain Res. 1997 May 23;757(2):285-90.

Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates.

Author information

1
University of Virginia, Department of Biology, Center for Biological Timing, Charlottesville 22903, USA. edh3f@virginia.edu

Abstract

The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a circadian pacemaker. This study used multimicroelectrode plates to measure extracellular action potential activity simultaneously from multiple sites within the cultured mouse SCN. Neurons within the isolated mouse SCN expressed a circadian rhythm in spontaneous firing rate for weeks in culture.

PMID:
9200759
DOI:
10.1016/s0006-8993(97)00337-5
[Indexed for MEDLINE]

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