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Acta Otolaryngol Suppl. 1997;527:128-30.

Adjuvant therapy with hydrolytic enzymes in recurrent laryngeal papillomatosis.

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Department of Otorhinolaryngology, P.J. Safárik University Hospital, Kosice, Slovak Republic.


The subject of this study is systemic enzymotherapy as adjuvant treatment in recurrent laryngeal papillomatosis. The authors analyze their observations of 5 adult patients with recurrent laryngeal papillomatosis when after surgical extirpation and subsequent application of peroral proteases there was a significant improvement of their clinical state and laboratory results. The patients have been disease-free from 10 to 18 months. In the authors' experience, the adjuvant enzymotherapy seems to be a suitable replacement of the supplementary treatment in larynx papillomatosis, and it promises to decrease the recurrence rate as well.

[Indexed for MEDLINE]

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