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Curr Biol. 1997 Jun 1;7(6):R369-72.

Microtubule dynamics: treadmilling comes around again.

Author information

1
Department of Biology, CB# 3280, 607 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina 27599, USA. waterman@email.unc.edu

Abstract

Although it is generally believed that microtubules have minus ends bound to the centrosome and free plus ends that exhibit dynamic instability, recent observations show that the minus ends can be free and that modulation of dynamic instability at both ends can result in treadmilling and flux in interphase cells.

PMID:
9197225
DOI:
10.1016/s0960-9822(06)00177-1
[Indexed for MEDLINE]
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