Format

Send to

Choose Destination
Nature. 1997 Jun 19;387(6635):773-6.

Double identity for proteins of the Bcl-2 family.

Author information

1
Burnham Institute, Program on Apoptosis and Cell Death Research, La Jolla, California 92037, USA.

Abstract

Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.

PMID:
9194558
DOI:
10.1038/42867
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center