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J Urol. 1977 Nov;118(5):757-60.

Topical instillation of doxorubicin hydrochloride in the treatment of recurring superficial transitional cell carcinoma of the bladder.


Thirteen patients with recurring stage A transitional cell carcinoma of the bladder were treated with monthly bladder instillations of doxorubicin hydrochloride. Follow-up at 3-month intervals has shown excellent control of tumor recurrence with complete remissions for up to 21 months in 2 patients. The median for remission in 8 of 13 patients has been 10 months. Two patients with bladder papillomatosis were treated successfully by the same method.

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