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Trends Microbiol. 1997 May;5(5):201-4.

Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?

Author information

1
Dept of Microbiology, New York University School of Medicine, NY 10016, USA. zychlinsky@saturn.med.nyu.edu

Abstract

Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.

PMID:
9160509
DOI:
10.1016/S0966-842X(97)01044-5
[Indexed for MEDLINE]

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