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Trends Microbiol. 1997 May;5(5):189-95.

RNA editing in kinetoplastid parasites: what to do with U.

Author information

1
Dept of Biochemistry, University of Amsterdam, The Netherlands.

Abstract

The editing of the mitochondrial RNAs of kinetoplastid protozoa is a bizarre form of transcript maturation that involves insertion and deletion of uridylate residues. Editing leads to the formation of translational initiation and termination codons, the correction of gene-encoded reading frame shifts and the creation of complete reading frames in mRNAs. It is therefore an essential step in mitochondrial gene expression.

PMID:
9160507
DOI:
10.1016/S0966-842X(97)01034-2
[Indexed for MEDLINE]

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