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Microb Drug Resist. 1996 Spring;2(1):105-12.

The convergence of murein recycling research with beta-lactamase research.

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1
Department of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts 02111, USA.

Abstract

The story of how investigation of Escherichia coli cell wall elongation evolved into a study of murein recycling and how this led to the discovery that ampG and ampD were required for both murein recycling and beta-lactamase regulation is chronicled. Preliminary information on two other genes believed to be involved in recycling, nagZ, the structural gene for beta-N-acetylglucosaminidase, and tpl, the presumed structural gene for the hypothetical tripeptide-adding enzyme, is presented. The possibility that recycling of murein fragments serves a signaling function is discussed.

PMID:
9158731
DOI:
10.1089/mdr.1996.2.105
[Indexed for MEDLINE]
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