Format

Send to

Choose Destination
See comment in PubMed Commons below
Neurology. 1997 May;48(5):1225-6.

A beneficial effect of oxandrolone in the treatment of Duchenne muscular dystrophy: a pilot study.

Author information

1
Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN 37212, USA.

Abstract

We treated 10 boys with Duchenne muscular dystrophy with oxandrolone, an anabolic steroid, for 3 months. The mean of the changes in the average muscle score was an improvement of 0.315 +/- 0.097. The expected mean change in muscle score after 3 months from natural history data is a loss of 0.1. The difference of 0.415 between the actual and expected values is significant at p < 0.01. This preliminary evidence suggests that oxandrolone treatment may provide a degree of functional benefit for children with Duchenne muscular dystrophy that is similar to that after prednisone administration.

PMID:
9153447
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center